{"id":6394,"date":"2026-04-23T15:00:00","date_gmt":"2026-04-23T07:00:00","guid":{"rendered":"https:\/\/nowserving.ph\/blog\/?p=6394"},"modified":"2026-04-22T19:33:27","modified_gmt":"2026-04-22T11:33:27","slug":"hemophilia-a-and-b","status":"publish","type":"post","link":"https:\/\/nowserving.ph\/blog\/hemophilia-a-and-b\/","title":{"rendered":"Difference Between Hemophilia A and B: Comparison and When to Visit a Doctor for Treatment"},"content":{"rendered":"\n

The World Federation of Hemophilia<\/a> estimates that over 1.2 million people worldwide have hemophilia, yet fewer than half are formally diagnosed. In a countrywhere access to specialist care and complete hospital equipment for treatment remains uneven outside Metro Manila<\/a>, knowing the difference between hemophilia A and B and how to manage it early matters.<\/p>\n\n\n\n

Both types cause serious bleeding from the underproduction of blood clotting proteins, but the missing protein is different in each case. That difference determines the replacement therapy a patient needs and whether emerging treatments like gene therapy apply. This guide covers the key differences between hemophilia A and B, symptoms, inheritance patterns, and when to visit a doctor for treatment.<\/p>\n\n\n\n

What Is Hemophilia?<\/h2>\n\n\n\n

Hemophilia is a rare genetic disorder where the blood cannot clot properly due to a deficiency in a specific clotting factor<\/a>. When bleeding starts, the body triggers a coagulation cascade, a sequence of proteins that work together to seal the wound. A missing or low-functioning protein in that chain means the clot forms slowly or not at all.<\/p>\n\n\n\n

\"hemophilia<\/figure>\n\n\n\n

Without treatment, even routine injuries can cause prolonged serious bleeding. Repeated bleeding into joints and muscles causes long-term complications including joint damage, chronic pain, and reduced mobility. In severe cases, internal bleeding can become life-threatening.<\/p>\n\n\n\n

Hemophilia A and B: The Significant Differences<\/h2>\n\n\n\n

The two most common types of hemophilia are caused by deficiencies in different clotting factors.<\/p>\n\n\n\n

Hemophilia A (Classic Hemophilia)<\/h3>\n\n\n\n

Hemophilia A is caused by a deficiency of Factor VIII (Factor 8). It is the most common type of hemophilia, affecting roughly 1 in 5,000 male births globally and accounting for 80 to 85 percent of all cases.<\/p>\n\n\n\n

Severity is classified by residual Factor VIII activity:<\/strong><\/p>\n\n\n\n